This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MAPRE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-71 amino acids from the N-terminal region of human MAPRE1.
MAPRE1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
MAPRE1
(Microtubule-Associated Protein, RP/EB Family, Member 1 (MAPRE1))
EB1 antibody, 5530600P05Rik antibody, AI462499 antibody, AI504412 antibody, AW260097 antibody, BIM1p antibody, D2Ertd459e antibody, Eb1 antibody, MAPRE1 antibody, mapre1l antibody, wu:fi33c06 antibody, zgc:55428 antibody, zgc:77807 antibody, mapre1 antibody, wu:fa01e12 antibody, wu:fc23e11 antibody, zgc:85755 antibody, MGC52508 antibody, eb1 antibody, xEB1B antibody, Mapre3 antibody, microtubule associated protein RP/EB family member 1 antibody, microtubule-associated protein, RP/EB family, member 1 antibody, microtubule-associated protein, RP/EB family, member 1a antibody, microtubule-associated protein, RP/EB family, member 1b antibody, microtubule associated protein RP/EB family member 1 L homeolog antibody, microtubule associated protein RP/EB family member 1 S homeolog antibody, MAPRE1 antibody, Mapre1 antibody, mapre1a antibody, mapre1b antibody, mapre1.L antibody, mapre1.S antibody
Background
The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.