This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This FBXL8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-83 amino acids from the N-terminal region of human FBXL8.
FBXL8
Reactivity: Human
ELISA
Host: Mouse
Monoclonal
unconjugated
Application Notes
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.47 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
FBXL8
(F-Box and Leucine-Rich Repeat Protein 8 (FBXL8))
FBXL8 antibody, zgc:123259 antibody, FBL8 antibody, RGD1566420 antibody, F-box and leucine rich repeat protein 8 antibody, F-box and leucine-rich repeat protein 8 antibody, F-box and leucine-rich repeat protein 8 L homeolog antibody, FBXL8 antibody, fbxl8 antibody, fbxl8.L antibody, Fbxl8 antibody
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class. It shares 78 % sequence identity with the mouse protein.