PDGFRL antibody (C-Term)

Catalog No. ABIN5534597

Product Details anti-PDGFRL Antibody

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Binding Specificity: AA 328-357, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This PDGFRL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-357 amino acids from the C-terminal region of human PDGFRL.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PDGFRL

Target: PDGFRL (Platelet-Derived Growth Factor Receptor-Like (PDGFRL))

Alternative Name: PDGFRL (PDGFRL Products)

Synonyms: zgc:56104 antibody, zgc:77677 antibody, MGC82397 antibody, PDGFRL antibody, pdgrl antibody, prlts antibody, MGC107901 antibody, PDGRL antibody, PRLTS antibody, 1110039P19Rik antibody, AV013190 antibody, platelet-derived growth factor receptor-like antibody, platelet derived growth factor receptor like L homeolog antibody, platelet derived growth factor receptor like antibody, pdgfrl antibody, pdgfrl.L antibody, PDGFRL antibody, Pdgfrl antibody

Background: PDGFRL bears significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in the PDGFRL gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests PDGFRL may function as a tumor suppressor.

Molecular Weight: 42 kDa

Gene ID: 5157

UniProt: Q15198

Pathways: Platelet-derived growth Factor Receptor Signaling