SH3BP1 antibody (AA 419-446)

Catalog No. ABIN5534682

Product Details anti-SH3BP1 Antibody

Target: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Binding Specificity: AA 419-446

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SH3BP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 419-446 amino acids from the Central region of human SH3BP1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SH3BP1

Target: SH3BP1 (SH3-Domain Binding Protein 1 (SH3BP1))

Alternative Name: SH3BP1 (SH3BP1 Products)

Synonyms: ARHGAP43 antibody, 3BP-1 antibody, SH3BP1 antibody, SH3 domain binding protein 1 antibody, SH3-domain binding protein 1 antibody, SH3 domain-binding protein 1 antibody, SH3BP1 antibody, Sh3bp1 antibody, LOC100398528 antibody

Background: SH3BP1 binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho-or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity).

Molecular Weight: 76 kDa

Gene ID: 23616

UniProt: Q9Y3L3