ZBTB7B antibody (C-Term)

Catalog No. ABIN5534847

Product Details anti-ZBTB7B Antibody

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Binding Specificity: AA 440-469, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB7B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This ZBTB7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-469 amino acids from the C-terminal region of human ZBTB7B.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ZBTB7B

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Alternative Name: ZBTB7B (ZBTB7B Products)

Synonyms: THPOK antibody, ZBTB15 antibody, ZFP-67 antibody, ZFP67 antibody, ZNF857B antibody, c-KROX antibody, hcKROX antibody, Thpok antibody, Zfp67 antibody, c-Krox antibody, ZBTB7B antibody, zbtb7b antibody, MGC130914 antibody, zinc finger and BTB domain containing 7B antibody, kruppel-related zinc finger protein hcKrox antibody, ZBTB7B antibody, Zbtb7b antibody, zbtb7b antibody

Background: ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

Molecular Weight: 58 kDa

Gene ID: 51043

UniProt: O15156