This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This KLRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-206 amino acids from the C-terminal region of human KLRC1.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
KLRC1
(Killer Cell Lectin-Like Receptor Subfamily C, Member 1 (KLRC1))
rNKG2A antibody, NKG2-A antibody, NKG2A antibody, KLRC1 antibody, CD159A antibody, NKG2 antibody, CD159a antibody, NKG2B antibody, killer cell lectin like receptor C1 antibody, NKG2-A/NKG2-B type II integral membrane protein-like antibody, killer cell lectin-like receptor subfamily C, member 3 antibody, killer cell lectin-like receptor subfamily C, member 1 antibody, Klrc1 antibody, KLRC1 antibody, NKG2A antibody, KLRC3 antibody
Background
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. This protein belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.