Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Immunogen
This CYP4B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-362 amino acids from the Central region of human CYP4B1.
CYP4B1
Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse, Bat, Hamster
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
2 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
CYP4B1
(Cytochrome P450, Family 4, Subfamily B, Polypeptide 1 (CYP4B1))
CYPIVB1 antibody, P-450HP antibody, cytochrome P450, family 4, subfamily B, polypeptide 1 antibody, CYP4B1-like isozyme short form antibody, cytochrome P450, family 4, subfamily B, polypeptide 1 L homeolog antibody, cytochrome P450 family 4 subfamily B member 1 antibody, cytochrome P450, family 4, subfamily b, polypeptide 1 antibody, cytochrome P450 family 4 subfamily B member 1 L homeolog antibody, CYP4B1 antibody, cyp4b1.L antibody, cyp4b1 antibody, Cyp4b1 antibody, cyp4b1.2.L antibody
Background
CYP4B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens, however, the specific function of the human protein has not been determined.