SOX8 antibody (AA 225-253)

Catalog No. ABIN5535011

Product Details anti-SOX8 Antibody

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Binding Specificity: AA 225-253

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX8 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SOX8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-253 amino acids from the Central region of human SOX8.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SOX8

Target: SOX8 (SRY (Sex Determining Region Y)-Box 8 (SOX8))

Alternative Name: SOX8 (SOX8 Products)

Synonyms: SRY-box 8 antibody, SRY box 8 antibody, SRY-box 8 L homeolog antibody, SRY (sex determining region Y)-box 8 antibody, SOX8 antibody, Sox8 antibody, sox8.L antibody

Background: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).

Molecular Weight: 47 kDa

Gene ID: 30812

UniProt: P57073

Pathways: Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development