CDK14 antibody (N-Term)

Catalog No. ABIN5535105

Product Details anti-CDK14 Antibody

Target: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Binding Specificity: AA 45-72, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK14 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Cdk14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-72 amino acids from the N-terminal region of mouse Cdk14.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CDK14

Target: CDK14 (Cyclin-Dependent Kinase 14 (CDK14))

Alternative Name: Cdk14 (CDK14 Products)

Synonyms: PFTK1 antibody, PFTAIRE1 antibody, Pftk1 antibody, mKIAA0834 antibody, pftaire1 antibody, pftk1 antibody, cyclin dependent kinase 14 antibody, cyclin-dependent kinase 14 antibody, cyclin-dependent kinase 14 L homeolog antibody, CDK14 antibody, Cdk14 antibody, cdk14.L antibody

Background: Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport (By similarity).

Molecular Weight: 53 kDa

Gene ID: 18647

UniProt: O35495