MAGEH1 antibody (C-Term)

Catalog No. ABIN5535518

Product Details anti-MAGEH1 Antibody

Target: MAGEH1 (Melanoma Antigen Family H, 1 (MAGEH1))

Binding Specificity: AA 186-218, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This MAGEH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-218 amino acids from the C-terminal region of human MAGEH1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MAGEH1

Target: MAGEH1 (Melanoma Antigen Family H, 1 (MAGEH1))

Alternative Name: MAGEH1 (MAGEH1 Products)

Synonyms: MAGEH1 antibody, APR-1 antibody, APR1 antibody, MAGEH antibody, 2010107K23Rik antibody, MAGE family member H1 antibody, melanoma antigen, family H, 1 antibody, MAGEH1 antibody, Mageh1 antibody

Background: Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Molecular Weight: 24 kDa

Gene ID: 28986

UniProt: Q9H213

Pathways: Neurotrophin Signaling Pathway