BHLHE22 antibody (AA 236-264)

Catalog No. ABIN5535550

Product Details anti-BHLHE22 Antibody

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Binding Specificity: AA 236-264

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHE22 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BHLHB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from the Central region of human BHLHB5.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for BHLHE22

Target: BHLHE22 (Basic Helix-Loop-Helix Family, Member E22 (BHLHE22))

Alternative Name: BHLHB5 (BHLHE22 Products)

Synonyms: bhlhb5 antibody, MGC145865 antibody, BHLHE22 antibody, Beta3.1 antibody, wu:fq25e11 antibody, zgc:64225 antibody, BHLHB5 antibody, Beta3 antibody, CAGL85 antibody, TNRC20 antibody, Bhlhb5 antibody, basic helix-loop-helix family member e22 antibody, basic helix-loop-helix family, member e22 antibody, bhlhe22 antibody, BHLHE22 antibody, Bhlhe22 antibody

Background: BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.

Molecular Weight: 37 kDa

Gene ID: 27319

UniProt: Q8NFJ8