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Caldesmon antibody (AA 428-457)

CALD1 Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5535572
  • Target See all Caldesmon (CALD1) Antibodies
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Binding Specificity
    • 26
    • 15
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 428-457
    Reactivity
    • 85
    • 82
    • 63
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 101
    • 19
    Rabbit
    Clonality
    • 84
    • 36
    Polyclonal
    Conjugate
    • 74
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Caldesmon antibody is un-conjugated
    Application
    • 73
    • 32
    • 31
    • 27
    • 26
    • 19
    • 17
    • 17
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This CALD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the Central region of human CALD1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CALD1 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Caldesmon (CALD1) (Caldesmon 1 (CALD1))
    Alternative Name
    CALD1 (CALD1 Products)
    Synonyms
    CDM antibody, H-CAD antibody, HCAD antibody, L-CAD antibody, LCAD antibody, NAG22 antibody, l-Cad antibody, 4833423D12Rik antibody, AI195384 antibody, AV071549 antibody, AW536160 antibody, C920027I18Rik antibody, CALD1 antibody, Caldesmon antibody, caldesmon 1 antibody, CALD1 antibody, Cald1 antibody
    Background
    CALD1 is a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction.
    Molecular Weight
    93 kDa
    Gene ID
    800
    UniProt
    Q05682
    Pathways
    Myometrial Relaxation and Contraction
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