BCAT1 antibody (AA 81-107)

Catalog No. ABIN5535721

Product Details anti-BCAT1 Antibody

Target: BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))

Binding Specificity: AA 81-107

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BCAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human BCAT1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for BCAT1

Target: BCAT1 (Branched Chain Amino-Acid Transaminase 1, Cytosolic (BCAT1))

Alternative Name: BCAT1 (BCAT1 Products)

Synonyms: fj66g02 antibody, zgc:73157 antibody, wu:fj66g02 antibody, Bcatc antibody, BCATC antibody, BCT1 antibody, ECA39 antibody, MECA39 antibody, PNAS121 antibody, PP18 antibody, BCATc antibody, Eca39 antibody, branched chain amino-acid transaminase 1, cytosolic antibody, branched chain amino acid transaminase 1 antibody, branched chain amino-acid transaminase 1, cytosolic L homeolog antibody, branched chain aminotransferase 1, cytosolic antibody, bcat1 antibody, BCAT1 antibody, bcat1.L antibody, Bcat1 antibody

Background: This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Molecular Weight: 43 kDa

Gene ID: 586

UniProt: P54687