CASC4 antibody (C-Term)

Catalog No. ABIN5535924

Product Details anti-CASC4 Antibody

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Binding Specificity: AA 336-365, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASC4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CASC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human CASC4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CASC4

Target: CASC4 (Cancer Susceptibility Candidate 4 (CASC4))

Alternative Name: CASC4 (CASC4 Products)

Synonyms: H63 antibody, D130060C09Rik antibody, VGFG2573 antibody, cancer susceptibility 4 antibody, cancer susceptibility candidate 4 antibody, cancer susceptibility 4 L homeolog antibody, CASC4 antibody, Casc4 antibody, casc4.L antibody

Background: The increased expression level of this gene is associated with HER-2/neu proto-oncogene overexpression. Amplification and resulting overexpression of this proto-oncogene are found in approximately 30 % of human breast and 20 % of human ovarian cancers. Further characterization of the product of this gene may yield insight into the fundamental biology and pathogenetic effects of HER-2/neu overexpression in human breast and ovarian cancer cells. Alternatively spliced variants encoding different isoforms have been identified for this gene.

Molecular Weight: 49 kDa

Gene ID: 113201

UniProt: Q6P4E1