AGL antibody (AA 357-387)

Catalog No. ABIN5535955

Product Details anti-AGL Antibody

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Binding Specificity: AA 357-387

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This AGL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-387 amino acids from the Central region of human AGL.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for AGL

Target: AGL (Amylo-alpha-1, 6-Glucosidase, 4-alpha-Glucanotransferase (AGL))

Alternative Name: AGL (AGL Products)

Synonyms: DDBDRAFT_0219237 antibody, DDBDRAFT_0234114 antibody, DDB_0219237 antibody, DDB_0234114 antibody, GDE antibody, 1110061O17Rik antibody, 9430004C13Rik antibody, 9630046L06Rik antibody, AI850929 antibody, C77197 antibody, amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase antibody, glycogen debranching enzyme antibody, glycogen debranching protein antibody, amylo-1,6-glucosidase, 4-alpha-glucanotransferase antibody, AGL antibody, agl antibody, MMAH_RS03870 antibody, Agl antibody

Background: AGL is a glycogen debrancher enzyme which is involved in glycogen degradation. This enzyme has two independent catalytic activities which occur at different sites on the protein: a 4-alpha-glucotransferase activity and a amylo-1,6-glucosidase activity. Mutations in the AGL gene are associated with glycogen storage disease although a wide range of enzymatic and clinical variability occurs which may be due to tissue-specific alternative splicing.

Molecular Weight: 175 kDa

Gene ID: 178

UniProt: P35573

Pathways: Cellular Glucan Metabolic Process