HuC/ELAVL3 antibody (N-Term)

Catalog No. ABIN5536045

Product Details anti-HuC/ELAVL3 Antibody

Target: HuC/ELAVL3 (ELAVL3) (ELAV-Like 3 (ELAVL3))

Binding Specificity: AA 71-99, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HuC/ELAVL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-99 amino acids from the N-terminal region of human ELAVL3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for HuC/ELAVL3

Target: HuC/ELAVL3 (ELAVL3) (ELAV-Like 3 (ELAVL3))

Alternative Name: ELAVL3 (ELAVL3 Products)

Synonyms: HuC antibody, elrc antibody, zHuC antibody, id:ibd1248 antibody, wu:fb77b03 antibody, HUC antibody, HUCL antibody, PLE21 antibody, Huc antibody, 2600009P04Rik antibody, mHuC antibody, elrC antibody, ELAV like neuron-specific RNA binding protein 3 antibody, ELAV like RNA binding protein 3 antibody, ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) antibody, ELAV like neuron-specific RNA binding protein 3 L homeolog antibody, elavl3 antibody, ELAVL3 antibody, Elavl3 antibody, elavl3.L antibody

Background: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Molecular Weight: 40 kDa

Gene ID: 1995

UniProt: Q14576