This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ETFDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human ETFDH.
ETFDH
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ETFQO antibody, MADD antibody, 0610010I20Rik antibody, AV001013 antibody, MGC81928 antibody, zgc:92093 antibody, wu:fa05a11 antibody, wu:fb71g06 antibody, MGC69479 antibody, DDBDRAFT_0206234 antibody, DDBDRAFT_0267019 antibody, DDB_0206234 antibody, DDB_0267019 antibody, ETF-QO antibody, electron transfer flavoprotein dehydrogenase antibody, electron transferring flavoprotein, dehydrogenase antibody, electron transfer flavoprotein dehydrogenase L homeolog antibody, electron-transferring-flavoprotein dehydrogenase antibody, electron transfer flavoprotein-ubiquinone oxidoreductase antibody, Electron-transferring-flavoprotein dehydrogenase antibody, ETFDH antibody, Etfdh antibody, etfdh.L antibody, etfdh antibody, CBU_1120 antibody, ZMO1184 antibody, RPE_4421 antibody, Daci_4310 antibody, Bphyt_2765 antibody, Dtpsy_1751 antibody, Za10_0145 antibody, Mesop_5359 antibody
Background
Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in the mitochondrial membrane. The protein is synthesized as a 67- kDa precursor which is targeted to mitochondria and processed in a single step to a 64- kDa mature form located in the mitochondrial membrane. Deficiency in electron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type II glutaricacidemia.