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LGR5 antibody (AA 689-719)

LGR5 Reactivity: Human, Mouse, Rat WB, FACS, IHC (p), IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5536141
  • Target See all LGR5 Antibodies
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    Binding Specificity
    • 16
    • 15
    • 11
    • 7
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 689-719
    Reactivity
    • 104
    • 56
    • 48
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 92
    • 13
    Rabbit
    Clonality
    • 81
    • 24
    Polyclonal
    Conjugate
    • 49
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGR5 antibody is un-conjugated
    Application
    • 78
    • 38
    • 21
    • 20
    • 17
    • 16
    • 14
    • 13
    • 9
    • 7
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LGR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-719 amino acids from human LGR5.
    Isotype
    IgG
    Top Product
    Discover our top product LGR5 Primary Antibody
  • Application Notes
    For FACS starting dilution is: 1:25

    For IHC-P starting dilution is: 1:25

    For WB starting dilution is: 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.28 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
    Alternative Name
    LGR5 (LGR5 Products)
    Synonyms
    lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody
    Background
    LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling. Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
    Molecular Weight
    100 kDa
    Gene ID
    8549
    UniProt
    O75473
    Pathways
    WNT Signaling
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