HEYL antibody (N-Term)

Catalog No. ABIN5536236

Product Details anti-HEYL Antibody

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Binding Specificity: AA 26-54, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HEYL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HEYL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human HEYL.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for HEYL

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Alternative Name: HEYL (HEYL Products)

Synonyms: HESR3 antibody, HEY3 antibody, HRT3 antibody, bHLHb33 antibody, Hey3 antibody, Hrt3 antibody, hesr3 antibody, fk74e12 antibody, wu:fk74e12 antibody, hes related family bHLH transcription factor with YRPW motif-like antibody, hairy/enhancer-of-split related with YRPW motif-like antibody, hes-related family bHLH transcription factor with YRPW motif-like antibody, HEYL antibody, Heyl antibody, heyl antibody

Background: This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq].

Molecular Weight: 35 kDa

Gene ID: 26508

UniProt: Q9NQ87

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling