LMTK2 antibody (AA 668-697)

Catalog No. ABIN5536370

Product Details anti-LMTK2 Antibody

Target: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Binding Specificity: AA 668-697

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMTK2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This LMTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 668-697 amino acids from the Central region of human LMTK2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LMTK2

Target: LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))

Alternative Name: LMTK2 (LMTK2 Products)

Synonyms: AATYK2 antibody, BREK antibody, KPI-2 antibody, KPI2 antibody, LMR2 antibody, cprk antibody, 2900041G10Rik antibody, A330101P12Rik antibody, aatyk2 antibody, lemur tyrosine kinase 2 antibody, LMTK2 antibody, Lmtk2 antibody

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families.

Molecular Weight: 165 kDa

Gene ID: 22853

UniProt: Q8IWU2

Pathways: RTK Signaling, Neurotrophin Signaling Pathway