MGAT2 antibody (C-Term)

Catalog No. ABIN5536393

Product Details anti-MGAT2 Antibody

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Binding Specificity: AA 409-439, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGAT2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MGAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-439 amino acids from the C-terminal region of human MGAT2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MGAT2

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Alternative Name: MGAT2 (MGAT2 Products)

Synonyms: CDG2A antibody, CDGS2 antibody, GLCNACTII antibody, GNT-II antibody, GNT2 antibody, CG7921 antibody, Dmel\\CG7921 antibody, GlcNAc-TII antibody, GlcNAcT2 antibody, dMGAT2 antibody, MGC89475 antibody, Gnt2 antibody, AA407964 antibody, CH73-301C19.1 antibody, zgc:162268 antibody, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase antibody, CG7921 gene product from transcript CG7921-RB antibody, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog antibody, mannoside acetylglucosaminyltransferase 2 antibody, MGAT2 antibody, Mgat2 antibody, mgat2.L antibody, mgat2 antibody

Background: MGAT2 (UDP-N-acetylglucosamine:alpha-6-D-mannoside-beta-1, 2-N-acetylglucosaminyltransferase II) is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in MGAT2 may lead to carbohydrate-deficient glycoprotein syndrome, type II.

Molecular Weight: 52 kDa

Gene ID: 4247

UniProt: Q10469