IARS2 antibody (AA 600-628)

Catalog No. ABIN5536491

Product Details anti-IARS2 Antibody

Target: IARS2 (Isoleucyl-tRNA Synthetase 2, Mitochondrial (IARS2))

Binding Specificity: AA 600-628

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This IARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 600-628 amino acids from the Central region of human IARS2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for IARS2

Target: IARS2 (Isoleucyl-tRNA Synthetase 2, Mitochondrial (IARS2))

Alternative Name: IARS2 (IARS2 Products)

Synonyms: RGD1311857 antibody, si:zc214p16.3 antibody, si:ch211-214p16.3 antibody, 2010002H18Rik antibody, C79125 antibody, ILERS antibody, ileRS antibody, isoleucyl-tRNA synthetase 2, mitochondrial antibody, isoleucine-tRNA synthetase 2, mitochondrial antibody, Iars2 antibody, IARS2 antibody, iars2 antibody

Background: IARS2 belongs to the class-I aminoacyl-tRNA synthetase family. Members of class I have two highly conserved sequence motifs. They aminoacylate at the 2'-OH of an adenosine nucleotide, and are usually monomeric or dimeric (one or two subunits, respectively). Both classes of aminoacyl-tRNA synthetases are multidomain proteins. The catalytic domains of all the aaRSs of a given class are found to be homologous to one another, while class I and class II aaRSs are unrelated to one another. The class I aaRSs have the ubiquitous Rossmann fold and have the antiparallel beta-strands architecture while the class II aaRSs have a unique fold made up of antiparallel beta-strands.

Molecular Weight: 114 kDa

Gene ID: 55699

UniProt: Q9NSE4