Leupaxin antibody (AA 229-257)

Catalog No. ABIN5536538

Product Details anti-Leupaxin Antibody

Target: Leupaxin (LPXN)

Binding Specificity: AA 229-257

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leupaxin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LPXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the Central region of human LPXN.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Leupaxin

Target: Leupaxin (LPXN)

Alternative Name: LPXN (LPXN Products)

Synonyms: LDPL antibody, 4933402K05Rik antibody, A530083L21Rik antibody, AV278559 antibody, MGC140379 antibody, leupaxin antibody, hypothetical protein antibody, Leupaxin antibody, LPXN antibody, Lpxn antibody, lpxn antibody, PAAG_03110 antibody, PGTG_11441 antibody

Background: The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 43 kDa

Gene ID: 9404

UniProt: O60711