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PSME1 antibody (C-Term)

PSME1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5536542
  • Target See all PSME1 Antibodies
    PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
    Binding Specificity
    • 15
    • 10
    • 8
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 220-249, C-Term
    Reactivity
    • 51
    • 41
    • 38
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 6
    • 1
    Rabbit
    Clonality
    • 54
    • 12
    Polyclonal
    Conjugate
    • 28
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSME1 antibody is un-conjugated
    Application
    • 51
    • 21
    • 20
    • 14
    • 14
    • 13
    • 9
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PSME1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the C-terminal region of human PSME1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PSME1 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
    Alternative Name
    PSME1 (PSME1 Products)
    Synonyms
    fk89d05 antibody, wu:fk89d05 antibody, IFI5111 antibody, PA28A antibody, PA28alpha antibody, REGalpha antibody, AW413925 antibody, PA28a antibody, proteasome activator subunit 1 antibody, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody, psme1 antibody, PSME1 antibody, Psme1 antibody
    Background
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring.
    Molecular Weight
    29 kDa
    Gene ID
    5720
    UniProt
    Q06323
    Pathways
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
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