FANCB antibody (AA 360-388)

Catalog No. ABIN5536609

Product Details anti-FANCB Antibody

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Binding Specificity: AA 360-388

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCB antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FANCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human FANCB.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for FANCB

Target: FANCB (Fanconi Anemia, Complementation Group B (FANCB))

Alternative Name: FANCB (FANCB Products)

Synonyms: FA2 antibody, FAAP90 antibody, FAAP95 antibody, FAB antibody, FACB antibody, BC022692 antibody, Fanconi anemia complementation group B antibody, Fanconi anemia, complementation group B antibody, FANCB antibody, Fancb antibody

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group B. Alternative splicing results in two transcript variants encoding the same protein.

Molecular Weight: 98 kDa

Gene ID: 2187

UniProt: Q8NB91

Pathways: DNA Damage Repair