IL5RA antibody (C-Term)

Catalog No. ABIN5536641

Product Details anti-IL5RA Antibody

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Binding Specificity: AA 391-420, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL5RA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL5RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the C-terminal region of human IL5RA.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for IL5RA

Target: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Alternative Name: IL5RA (IL5RA Products)

Synonyms: MGC86517 antibody, IL5RA antibody, il5r antibody, cdw125 antibody, hsil5r3 antibody, gpIL-5ra antibody, CD125 antibody, CDw125 antibody, HSIL5R3 antibody, IL5R antibody, Il5r antibody, interleukin 5 receptor subunit alpha L homeolog antibody, interleukin 5 receptor subunit alpha antibody, interleukin 5 receptor, alpha antibody, il5ra.L antibody, IL5RA antibody, il5ra antibody, Il5ra antibody

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Molecular Weight: 48 kDa

Gene ID: 3568

UniProt: Q01344

Pathways: JAK-STAT Signaling