This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This LRIG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 801-829 amino acids from the C-terminal region of human LRIG1.
Lrig1
Reactivity: Human, Mouse, Rat
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
Alexa Fluor 488
Application Notes
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
Lrig1
(Leucine-Rich Repeats and Immunoglobulin-Like Domains 1 (Lrig1))
LIG-1 antibody, LIG1 antibody, D6Bwg0781e antibody, Img antibody, leucine rich repeats and immunoglobulin like domains 1 antibody, leucine-rich repeats and immunoglobulin-like domains 1 antibody, LRIG1 antibody, Lrig1 antibody
Background
LRIG1 act as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.