TBXAS1 antibody (AA 226-257)

Catalog No. ABIN5536835

Product Details anti-TBXAS1 Antibody

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Binding Specificity: AA 226-257

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBXAS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CYP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 226-257 amino acids from the Central region of human CYP5A1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TBXAS1

Target: TBXAS1 (thromboxane A Synthase 1 (Platelet) (TBXAS1))

Alternative Name: CYP5A1 (TBXAS1 Products)

Synonyms: thas antibody, TBXAS1 antibody, wu:fk19d08 antibody, zgc:136708 antibody, BDPLT14 antibody, CYP5 antibody, CYP5A1 antibody, GHOSAL antibody, THAS antibody, TS antibody, TXAS antibody, TXS antibody, thromboxane-A synthase antibody, Thromboxane-A synthase antibody, thromboxane A synthase 1 antibody, thromboxane A synthase 1 (platelet) antibody, thromboxane A synthase 1, platelet antibody, PTRG_00454 antibody, PTRG_06796 antibody, thas antibody, TBXAS1 antibody, tbxas1 antibody, Tbxas1 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 61 kDa

Gene ID: 6916

UniProt: P24557