NDUFV1 antibody (N-Term)

Catalog No. ABIN5537188

Product Details anti-NDUFV1 Antibody

Target: NDUFV1 (NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1))

Binding Specificity: AA 21-50, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFV1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NDUFV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 amino acids from the N-terminal region of human NDUFV1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NDUFV1

Target: NDUFV1 (NADH Dehydrogenase (Ubiquinone) Flavoprotein 1, 51kDa (NDUFV1))

Alternative Name: NDUFV1 (NDUFV1 Products)

Synonyms: GB17095 antibody, uqor1 antibody, DDBDRAFT_0188174 antibody, DDBDRAFT_0191420 antibody, DDB_0188174 antibody, DDB_0191420 antibody, wu:fc01f01 antibody, wu:fc12f12 antibody, zgc:86620 antibody, CI-51kD antibody, CI-51K antibody, CI51KD antibody, UQOR1 antibody, NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial antibody, NADH:ubiquinone oxidoreductase core subunit V1 antibody, NADH dehydrogenase ubiquinone flavoprotein 1 antibody, NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa antibody, NADH dehydrogenase (ubiquinone) flavoprotein 1 antibody, NADH:ubiquinone oxidoreductase core subunit V1 L homeolog antibody, LOC408367 antibody, NDUFV1 antibody, ndufv1 antibody, Ndufv1 antibody, LOC100179486 antibody, ndufv1.L antibody

Background: The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I, a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction, a syndrome that occurs in approximately 1 in 10,000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molecular Weight: 51 kDa

Gene ID: 4723

UniProt: P49821