PDE4A antibody (N-Term)

Catalog No. ABIN5537287

Product Details anti-PDE4A Antibody

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Binding Specificity: AA 32-61, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PDE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human PDE4A.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PDE4A

Target: PDE4A (phosphodiesterase 4A, CAMP-Specific (PDE4A))

Alternative Name: PDE4A (PDE4A Products)

Synonyms: pde4 antibody, dpde2 antibody, pde46 antibody, PDE4A antibody, Pde4a antibody, D9Ertd60e antibody, Dpde2 antibody, DPDE2 antibody, PDE4 antibody, PDE46 antibody, PHOSA antibody, phosphodiesterase 4A S homeolog antibody, phosphodiesterase 4A, cAMP-specific antibody, phosphodiesterase 4A antibody, phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) antibody, cAMP-specific 3',5'-cyclic phosphodiesterase 4A antibody, phosphodiesterase 4A, cAMP specific antibody, phosphodiesterase 4C antibody, pde4a.S antibody, pde4a antibody, PDE4A antibody, LOC100009247 antibody, Pde4a antibody, PDE4C antibody

Background: Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE (summary by Milatovich et al., 1994 [PubMed 8009369]).

Molecular Weight: 98 kDa

Gene ID: 5141

UniProt: P27815

Pathways: cAMP Metabolic Process