PUM1 antibody (AA 62-91)

Catalog No. ABIN5537383

Product Details anti-PUM1 Antibody

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Binding Specificity: AA 62-91

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PUM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 amino acids from human PUM1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PUM1

Target: PUM1 (Pumilio Homolog 1 (PUM1))

Alternative Name: PUM1 (PUM1 Products)

Synonyms: fb96a03 antibody, pumilio1 antibody, si:ch211-285e16.1 antibody, wu:fb96a03 antibody, wu:fb96a08 antibody, zgc:63671 antibody, PUM1 antibody, DKFZp459K0627 antibody, AA517475 antibody, Pumm antibody, mKIAA0099 antibody, HSPUM antibody, PUMH antibody, PUMH1 antibody, PUML1 antibody, pumilio RNA-binding family member 1 antibody, pumilio RNA binding family member 1 antibody, pum1 antibody, PUM1 antibody, Pum1 antibody

Background: PUM1 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.

Molecular Weight: 126 kDa

Gene ID: 9698

UniProt: Q14671