P2RX3 antibody (C-Term)

Catalog No. ABIN5537429

Product Details anti-P2RX3 Antibody

Target: P2RX3 (Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3))

Binding Specificity: AA 330-356, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This P2RX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-356 amino acids from the C-terminal region of human P2RX3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for P2RX3

Target: P2RX3 (Purinergic Receptor P2x, Ligand-Gated Ion Channel, 3 (P2RX3))

Alternative Name: P2RX3 (P2RX3 Products)

Synonyms: P2X3 antibody, 4930513E20Rik antibody, P2RX3 antibody, fb99b08 antibody, p2rx3 antibody, p2x3 antibody, wu:fb99b08 antibody, zP2X3 antibody, zfP2X3 antibody, p2xr3.2 antibody, zP2X3.2 antibody, zgc:110486 antibody, purinergic receptor P2X 3 antibody, purinergic receptor P2X, ligand-gated ion channel, 3 antibody, purinergic receptor P2X, ligand-gated ion channel, 3a antibody, purinergic receptor P2X, ligand-gated ion channel, 3b antibody, P2RX3 antibody, P2rx3 antibody, p2rx3a antibody, p2rx3b antibody

Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Molecular Weight: 44 kDa

Gene ID: 5024

UniProt: P56373