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RASGRF1 antibody (AA 907-936)

RASGRF1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5537439
  • Target See all RASGRF1 Antibodies
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    Binding Specificity
    • 15
    • 12
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 907-936
    Reactivity
    • 26
    • 25
    • 22
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 50
    Rabbit
    Clonality
    • 50
    Polyclonal
    Conjugate
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RASGRF1 antibody is un-conjugated
    Application
    • 33
    • 21
    • 14
    • 13
    • 13
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This RASGRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 907-936 amino acids from human RASGRF1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product RASGRF1 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.39 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))
    Alternative Name
    RASGRF1 (RASGRF1 Products)
    Synonyms
    CDC25 antibody, CDC25L antibody, GNRP antibody, GRF1 antibody, GRF55 antibody, H-GRF55 antibody, PP13187 antibody, ras-GRF1 antibody, AI844718 antibody, CDC25Mm antibody, Grf1 antibody, Grfbeta antibody, P190-A antibody, Ras-GRF1 antibody, p190 antibody, p190RhoGEF antibody, cdc25 antibody, rasgrf1 antibody, Ras protein specific guanine nucleotide releasing factor 1 antibody, RAS protein-specific guanine nucleotide-releasing factor 1 antibody, Ras protein specific guanine nucleotide releasing factor 1 S homeolog antibody, si:ch211-234p18.3 antibody, RASGRF1 antibody, Rasgrf1 antibody, rasgrf1.S antibody, si:ch211-234p18.3 antibody, rasgrf1 antibody
    Background
    RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
    Molecular Weight
    145 kDa
    Gene ID
    5923
    UniProt
    Q13972
    Pathways
    RTK Signaling, Cell Division Cycle, M Phase
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