SIN3A antibody (C-Term)

Catalog No. ABIN5537533

Product Details anti-SIN3A Antibody

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Binding Specificity: AA 1078-1106, C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIN3A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Sin3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1106 amino acids from the C-terminal region of mouse Sin3a.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SIN3A

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Alternative Name: Sin3a (SIN3A Products)

Synonyms: AW553200 antibody, Sin3 antibody, mKIAA4126 antibody, mSin3A antibody, zgc:162128 antibody, SIN3A antibody, SIN3 transcription regulator family member A antibody, transcriptional regulator, SIN3A (yeast) antibody, paired amphipathic helix protein Sin3a antibody, SIN3 transcription regulator family member Aa antibody, SIN3A antibody, Sin3a antibody, LOC100641919 antibody, sin3aa antibody, LOC100439524 antibody

Background: Sin3a acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.

Molecular Weight: 145 kDa

Gene ID: 20466

UniProt: Q60520

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha