CCDC99 antibody (C-Term)

Catalog No. ABIN5537551

Product Details anti-CCDC99 Antibody

Target: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Binding Specificity: AA 459-488, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC99 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CCDC99 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-488 amino acids from the C-terminal region of human CCDC99.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.49 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CCDC99

Target: CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))

Alternative Name: CCDC99 (CCDC99 Products)

Synonyms: CCDC99 antibody, CG15415 antibody, Dmel\\CG15415 antibody, SPINDLY antibody, ccdc99 antibody, 1700018I02Rik antibody, 2600001J17Rik antibody, 2810049B11Rik antibody, AA409762 antibody, Ccdc99 antibody, RGD1306908 antibody, ccdc99-a antibody, ccdc99-b antibody, spdl1-a antibody, spdl1-b antibody, spdl1 antibody, spindle apparatus coiled-coil protein 1 antibody, CG15415 gene product from transcript CG15415-RB antibody, Tetratricopeptide repeat (TPR)-like superfamily protein antibody, spindle apparatus coiled-coil protein 1 L homeolog antibody, spindle apparatus coiled-coil protein 1 S homeolog antibody, SPDL1 antibody, Spindly antibody, SPY antibody, spdl1 antibody, Spdl1 antibody, spdl1.L antibody, spdl1.S antibody

Background: CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.

Molecular Weight: 70 kDa

Gene ID: 54908

UniProt: Q96EA4