ORC5 antibody (AA 227-256)

Catalog No. ABIN5537713

Product Details anti-ORC5 Antibody

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Binding Specificity: AA 227-256

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ORC5L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human ORC5L.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ORC5

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Alternative Name: ORC5L (ORC5 Products)

Synonyms: Orc5l antibody, BG:DS00941.8 antibody, CG7833 antibody, D-orc5 antibody, DmORC5 antibody, DmOrc5 antibody, Dmel\\CG7833 antibody, ORC antibody, ORC5 antibody, br39 antibody, dORC5 antibody, l(2)34Df antibody, l(2)br39 antibody, orc5 antibody, orc5l antibody, wu:fb62d08 antibody, zgc:77827 antibody, ORC5L antibody, DDBDRAFT_0191826 antibody, DDBDRAFT_0233112 antibody, DDB_0191826 antibody, DDB_0233112 antibody, ORC5P antibody, ORC5T antibody, AL033327 antibody, MmORC5 antibody, origin recognition complex, subunit 5 antibody, Origin recognition complex subunit 5 antibody, origin recognition complex subunit 5 antibody, Orc5 antibody, orc5 antibody, ORC5 antibody, orcE antibody

Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

Molecular Weight: 50 kDa

Gene ID: 5001

UniProt: O43913

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA