MRGBP antibody (AA 46-75)

Catalog No. ABIN5537736

Product Details anti-MRGBP Antibody

Target: MRGBP (MRG-Binding Protein (MRGBP))

Binding Specificity: AA 46-75

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRGBP antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MRGBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the Central region of human MRGBP.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MRGBP

Target: MRGBP (MRG-Binding Protein (MRGBP))

Alternative Name: MRGBP (MRGBP Products)

Synonyms: C20orf20 antibody, Eaf7 antibody, MRG15BP antibody, URCC4 antibody, c20orf20 antibody, zgc:73167 antibody, 1600027N09Rik antibody, AW060503 antibody, C80444 antibody, MRG domain binding protein antibody, MRG/MORF4L-binding protein antibody, MRG-binding protein antibody, putative mrg-binding protein antibody, MRG/MORF4L binding protein antibody, MRGBP antibody, LOC5577096 antibody, CpipJ_CPIJ006487 antibody, CpipJ_CPIJ017611 antibody, Smp_130630 antibody, mrgbp antibody, Mrgbp antibody

Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Molecular Weight: 22 kDa

Gene ID: 55257

UniProt: Q9NV56