Nyctalopin antibody (N-Term)

Catalog No. ABIN5537867

Product Details anti-Nyctalopin Antibody

Target: Nyctalopin (NYX)

Binding Specificity: AA 53-80, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nyctalopin antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NYX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NYX.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Nyctalopin

Target: Nyctalopin (NYX)

Alternative Name: NYX (NYX Products)

Synonyms: MGC84276 antibody, CLRP antibody, CSNB1 antibody, CSNB1A antibody, CSNB4 antibody, NBM1 antibody, CLNP antibody, nob antibody, RGD1561300 antibody, nyctalopin antibody, nyctalopin L homeolog antibody, uncharacterized LOC491837 antibody, NYX antibody, nyx.L antibody, LOC491837 antibody, nyx antibody, Nyx antibody

Background: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq].

Molecular Weight: 52 kDa

Gene ID: 60506

UniProt: Q9GZU5