MMS19 antibody (AA 411-437)

Catalog No. ABIN5537935

Product Details anti-MMS19 Antibody

Target: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Binding Specificity: AA 411-437

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMS19 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MMS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 411-437 amino acids from the Central region of human MMS19.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.35 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MMS19

Target: MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))

Alternative Name: MMS19 (MMS19 Products)

Synonyms: MET18 antibody, MMS19L antibody, hMMS19 antibody, 2410001K24Rik antibody, 2610042O15Rik antibody, AI316855 antibody, C79368 antibody, C86341 antibody, Mms19l antibody, mms19 antibody, mms19l antibody, MMS19 homolog, cytosolic iron-sulfur assembly component antibody, MMS19 (MET18 S. cerevisiae) antibody, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antibody, MMS19 antibody, Mms19 antibody, mms19.L antibody

Background: MMS19 may play a role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription by interacting with ERCC2/XPD and ERCC3/XPB helicases, both subunits of NER-transcription factor TFIIH. May also function as a transcriptional coactivator of estrogen receptor (ER). May be involved in regulation of ER activity by bridging TFIIH with ER or may facilitate TFIIH-mediated phosphorylation of ER in specific promoters and cell types.

Molecular Weight: 113 kDa

Gene ID: 64210

UniProt: Q96T76

Pathways: Nuclear Hormone Receptor Binding