NPHP3 antibody (N-Term)

Catalog No. ABIN5537955

Product Details anti-NPHP3 Antibody

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Binding Specificity: AA 144-173, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NPHP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human NPHP3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NPHP3

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Alternative Name: NPHP3 (NPHP3 Products)

Synonyms: si:dkey-56l10.1 antibody, MKS7 antibody, NPH3 antibody, RHPD antibody, 3632410F03Rik antibody, AI550417 antibody, C230078J01 antibody, D330020E01Rik antibody, pcy antibody, RGD1563856 antibody, nephronophthisis 3 antibody, nephrocystin 3 antibody, nephronophthisis 3 (adolescent) antibody, nphp3 antibody, NPHP3 antibody, Nphp3 antibody

Background: This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine ligase (TTL) domain, and a tetratrico peptide repeat (TPR) domain. The encoded protein interacts with nephrocystin and may function in renal tubular development and function. Mutations in this gene are associated with nephronophthisis type 3. Multiple splice variants have been described but their full-length nature has not been determined.

Molecular Weight: 151 kDa

Gene ID: 27031

UniProt: Q7Z494

Pathways: cAMP Metabolic Process