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MYSM1 antibody (N-Term)

MYSM1 Reactivity: Human, Mouse WB, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5538020
  • Target See all MYSM1 Antibodies
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Binding Specificity
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 111-139, N-Term
    Reactivity
    • 35
    • 18
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 35
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYSM1 antibody is un-conjugated
    Application
    • 22
    • 21
    • 14
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MYSM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-139 amino acids from the N-terminal region of human MYSM1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product MYSM1 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))
    Alternative Name
    MYSM1 (MYSM1 Products)
    Synonyms
    2A-DUB antibody, 2ADUB antibody, RP4-592A1.1 antibody, C130067A03Rik antibody, C530050H10Rik antibody, RGD1311787 antibody, 2adub antibody, Myb like, SWIRM and MPN domains 1 antibody, myb-like, SWIRM and MPN domains 1 antibody, Myb like, SWIRM and MPN domains 1 L homeolog antibody, MYSM1 antibody, Mysm1 antibody, mysm1.L antibody
    Background
    Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
    Molecular Weight
    95 kDa
    Gene ID
    114803
    UniProt
    Q5VVJ2
    Pathways
    Chromatin Binding
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