MRPS11 antibody (AA 42-69)

Catalog No. ABIN5538188

Product Details anti-MRPS11 Antibody

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Binding Specificity: AA 42-69

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPS11 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MRPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-69 amino acids from the Central region of human MRPS11.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for MRPS11

Target: MRPS11 (Mitochondrial Ribosomal Protein S11 (MRPS11))

Alternative Name: MRPS11 (MRPS11 Products)

Synonyms: RGD1559901 antibody, HCC-2 antibody, 0710005I03Rik antibody, C79873 antibody, mitochondrial ribosomal protein S11 antibody, Mrps11 antibody, MRPS11 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms.

Molecular Weight: 21 kDa

Gene ID: 64963

UniProt: P82912