SIKE1 antibody (N-Term)

Catalog No. ABIN5538316

Product Details anti-SIKE1 Antibody

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Binding Specificity: AA 36-63, N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIKE1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.38 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for SIKE1

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Alternative Name: Sike1 (SIKE1 Products)

Synonyms: SIKE antibody, 2810005O12Rik antibody, 5730470L24Rik antibody, AI450236 antibody, AI839862 antibody, Sike antibody, Sikeb antibody, RGD1311316 antibody, suppressor of IKBKE 1 antibody, SIKE1 antibody, Sike1 antibody

Background: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity).

Molecular Weight: 24 kDa

Gene ID: 66641

UniProt: Q9CPR7