INSC antibody (AA 410-437)

Catalog No. ABIN5538778

Product Details anti-INSC Antibody

Target: INSC (Inscuteable Homolog (INSC))

Binding Specificity: AA 410-437

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INSC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This INSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the Central region of human INSC.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for INSC

Target: INSC (Inscuteable Homolog (INSC))

Alternative Name: INSC (INSC Products)

Synonyms: 3830422K02Rik antibody, C730020D23 antibody, RGD1311379 antibody, INSC, spindle orientation adaptor protein antibody, inscuteable homolog (Drosophila) antibody, INSC antibody, Insc antibody

Background: In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).

Molecular Weight: 63 kDa

Gene ID: 387755

UniProt: Q1MX18