AMAC1L2 antibody (C-Term)

Catalog No. ABIN5539088

Product Details anti-AMAC1L2 Antibody

Target: AMAC1L2 (SLC35G5) (Solute Carrier Family 35, Member G5 (SLC35G5))

Binding Specificity: AA 323-351, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMAC1L2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AMACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human AMACR.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for AMAC1L2

Target: AMAC1L2 (SLC35G5) (Solute Carrier Family 35, Member G5 (SLC35G5))

Alternative Name: AMAC (SLC35G5 Products)

Synonyms: AMAC antibody, AMAC1L2 antibody, solute carrier family 35 member G5 antibody, SLC35G5 antibody

Background: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.

Molecular Weight: 42 kDa

Gene ID: 23600

UniProt: Q9UHK6