Transportin 1 antibody (N-Term)

Catalog No. ABIN5539321

Product Details anti-Transportin 1 Antibody

Target: Transportin 1 (TNPO1)

Binding Specificity: AA 47-74, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transportin 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-74 amino acids from the N-terminal region of human TNPO1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Transportin 1

Target: Transportin 1 (TNPO1)

Alternative Name: TNPO1 (TNPO1 Products)

Synonyms: IPO2 antibody, KPNB2 antibody, MIP antibody, MIP1 antibody, TRN antibody, TNPO1 antibody, AU021749 antibody, D13Ertd688e antibody, Kpnb2 antibody, ATTRN1 antibody, F12A24.13 antibody, F12A24_13 antibody, TRANSPORTIN 1 antibody, transportin 1 antibody, DKFZp469O204 antibody, transportin 1 antibody, transportin-1 antibody, transportin 1 S homeolog antibody, TNPO1 antibody, LOC738932 antibody, tnpo1 antibody, Tnpo1 antibody, tnpo1.S antibody, TRN1 antibody

Background: TNPO1 comprises the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins.

Molecular Weight: 102 kDa

Gene ID: 3842

UniProt: Q92973

Pathways: PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process, Protein targeting to Nucleus, CXCR4-mediated Signaling Events