PDE4B antibody (C-Term)

Catalog No. ABIN5539878

Product Details anti-PDE4B Antibody

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PDE4B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: PDE4B

Sequence: IDIATEDKSP VDT

Specificity: This antibody is expected to recognize all reported isoforms (NP_002591.2, NP_001032416.1, NP_001032417.1).

Cross-Reactivity: Human, Mouse

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 98 kDa band observed in Human Uterus lysates (calculated MW of 83.3 kDa according to NP_002591.2). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Méhats et al, Endocrinology. 1999

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for PDE4B

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Alternative Name: PDE4B (PDE4B Products)

Synonyms: dpde4 antibody, pde4b5 antibody, pdeivb antibody, Dpde4 antibody, R74983 antibody, dunce antibody, PDE4/IVb antibody, Pde4B1 antibody, Pde4B2 antibody, Pde4B3 antibody, Pde4B4 antibody, DPDE4 antibody, PDE4B5 antibody, PDEIVB antibody, phosphodiesterase 4B antibody, phosphodiesterase 4B, cAMP specific antibody, phosphodiesterase 4B S homeolog antibody, pde4b antibody, PDE4B antibody, Pde4b antibody, pde4b.S antibody

Background: PDE4B, phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila), DPDE4, PDEIVB, Phosphodiesterase-4B, cAMP-specific (dunce (Drosophila)-homolog, phosphodiesterase 4B, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase

Gene ID: 5142, 18578

NCBI Accession: NP_002591, NP_001032416, NP_001032417

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction