REXO2 antibody (AA 26-237)

Catalog No. ABIN5540650

Product Details anti-REXO2 Antibody

Target: REXO2 (REX2, RNA Exonuclease 2 Homolog (REXO2))

Binding Specificity: AA 26-237

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This REXO2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Protein-A affinity chromatography

Immunogen: Recombinant human REXO 2 (26-237aa) purified from E. coli

Clone: AT59D9

Isotype: IgG2b

Application Details

Application Notes: The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4 containing 0.02 % Sodium Azide and 10 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for REXO2

Target: REXO2 (REX2, RNA Exonuclease 2 Homolog (REXO2))

Alternative Name: rexo2 (REXO2 Products)

Synonyms: SMFN antibody, REXO2 antibody, zgc:73191 antibody, 1810038D15Rik antibody, AW107347 antibody, Sfn antibody, Smfn antibody, REX2 antibody, RFN antibody, SFN antibody, RNA exonuclease 2 antibody, small fragment nuclease antibody, REXO2 antibody, smfn antibody, Rexo2 antibody

Background: REX2, RNA exonuclease 2 homolog (S. cerevisiae), also known as REXO2, is an enzyme which in humans is encoded by the REXO2 gene. Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair that also may be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mono-nucleotides in a sequential manner.

UniProt: Q9Y3B8