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CENPQ antibody

CENPQ Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Horse, Macaque WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN401060
  • Target See all CENPQ Antibodies
    CENPQ (Centromere Protein Q (CENPQ))
    Reactivity
    Human, Mouse, Rat, Pig, Cow, Dog, Horse, Macaque
    Host
    • 14
    • 1
    Rabbit
    Clonality
    • 14
    • 1
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CENPQ antibody is un-conjugated
    Application
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is specific for CENP-Q protein.
    Cross-Reactivity (Details)
    Species reactivity (expected):Macaque, Horse, Bovine, Canine, Porcine, Mouse, Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography on protein A
    Immunogen
    Prepared from whole rabbit serum produced by repeated immunizations with full-length human CENP-Q recombinant protein
    Isotype
    IgG
    Top Product
    Discover our top product CENPQ Primary Antibody
  • Application Notes
    ELISA: 1: 20,000 - 1: 30,000. Immunofluorescence. Western Blot: 1: 2,000 - 1: 2,500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.15 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
  • Target
    CENPQ (Centromere Protein Q (CENPQ))
    Alternative Name
    CENP-Q (CENPQ Products)
    Synonyms
    C6orf139 antibody, CENP-Q antibody, 2610528M18Rik antibody, centromere protein Q antibody, CENPQ antibody, cenpq antibody, Cenpq antibody
    Background
    Cenp-Q (also known as centromere protein Q or CENPQ) is a nuclear/centromeric protein that is one of the critical components that constitutes the CENP-O complex at the kinetochores and appears to stabilize PBIP1/CENP-U(50)/MLF1IP in the complex. This complex is important for proper recruitment of polo-like kinase 1 (Plk1) to the mitotic kinetochores. A failure in this process results in improper microtubule attachment to the kinetochores and chromosome missegregation that ultimately lead to aneuploidy.Synonyms: C6orf139, CENPQ, Centromere protein Q, chromosome 6 open reading frame 139
    Gene ID
    55166
    NCBI Accession
    NP_060602
    UniProt
    Q7L2Z9
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