HUS1B antibody (AA 104-117)

Catalog No. ABIN401265

Product Details anti-HUS1B Antibody

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Binding Specificity: AA 104-117

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HUS1B antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is directed against Hus1B protein.

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to amino acids 104-117 of human Hus1B protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/20000 - 1/100000. Western Blot: 1/500 - 1/5000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.75 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for HUS1B

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Alternative Name: HUS1B (HUS1B Products)

Synonyms: HUS1B antibody, RP11-532F6.1 antibody, HUS1 checkpoint clamp component B antibody, HUS1B antibody, Hus1b antibody

Background: The protein encoded by the Hus1B gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the checkpoint protein RAD1 but not with RAD9. Over expression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to HUS1. Hus1B is expressed strongly in testis, less in spleen, thymus, prostate, colon and leukocytes.Synonyms: Checkpoint protein HUS1B, HUS-1B, hHUS1B

Gene ID: 135458

NCBI Accession: NP_683762

UniProt: Q8NHY5